Matthew Perry cause of death: The Los Angeles County medical examiner’s office revealed on Friday that the late “Friends” actor’s death in October was an accident due to “acute effects of ketamine.” The main causes were drowning, coronary artery disease, and the effects of buprenorphine.
The ketamine in his system at the time of death could not have been from that infusion therapy since the half-life of ketamine is 3 to 4 hours or less.
According to his autopsy report, Perry was found alive by his live-in personal assistant that afternoon after returning from a pickleball game.